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Dirucotide

Cat. No. M31351

All AbMole products are for research use only, cannot be used for human consumption.

Dirucotide Structure
Synonym:

MBP8298

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Quality Control & Documentation
Biological Activity

Dirucotide (MBP8298) is a 17 amino acid synthetic peptide with a sequence identical to that of some human myelin basic proteins, and an MBP modulator. It can be used in the study of autoimmune diseases of the central nervous system such as multiple sclerosis (MS).

Chemical Information
Molecular Weight 2013.26
Formula C92H141N25O26
CAS Number 152074-97-0
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] George Deraos, et al. Brain Sci. Design of Linear and Cyclic Mutant Analogues of Dirucotide Peptide (MBP82⁻98) against Multiple Sclerosis: Conformational and Binding Studies to MHC Class II

[2] Leslie Boudesocque, et al. J Chromatogr A. Purification of dirucotide, a synthetic 17-aminoacid peptide, by ion exchange centrifugal partition chromatography

[3] Eric W Loo, et al. Cell Immunol. High dose antigen treatment with a peptide epitope of myelin basic protein modulates T cells in multiple sclerosis patients

[4] Paulo Fontoura, et al. Results Probl Cell Differ. Multiple sclerosis therapies: molecular mechanisms and future

[5] No authors listed. Drug News Perspect. Molecule of the month. Dirucotide

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Keywords: Dirucotide, MBP8298 supplier, inhibitors, activators

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