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Dipotassium hydrogen phosphate

Cat. No. M42770
Dipotassium hydrogen phosphate Structure
Size Price Availability Quantity
250g USD 66  USD66 In stock
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Quality Control & Documentation
  • Purity: ≥99.0%, for molecular biology
  • COA
  • MSDS
Biological Activity

Dipotassium hydrogen phosphate is a highly water-soluble salt which is often used as a fertilizer, food additive and buffering agent.

Chemical Information
Molecular Weight 174.18
Formula K2HPO4
CAS Number 7758-11-4
Form Solid
Solubility (25°C) Soluble in water
Storage 4°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Kazushi Nishimura et al. Anal Sci. Observation of the phase-separation multiphase flow using a polyethylene glycol/phosphate mixed solutions and the aqueous two-phase distribution of red blood cells in the flow system

[2] Julia M Poleschinski et al. J Avian Med Surg. A Novel Dipotassium Hydrogen Phosphate Phantom for Calibrating Computed Tomographic Bone Density Measurements in Birds

[3] Yuanchao Pei et al. J Chromatogr A. Partitioning behavior of amino acids in aqueous two-phase systems formed by imidazolium ionic liquid and dipotassium hydrogen phosphate

[4] David W Newton et al. Am J Health Syst Pharm. Calcium and phosphate compatibility: revisited again

[5] N C Martin et al. Sci Justice. The use of phosphate buffered saline for the recovery of cells and spermatozoa from swabs

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