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Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .
| Molecular Weight | 132.11 |
| Formula | C5H8O4 |
| CAS Number | 108-59-8 |
| Form | Liquid (density 1.156 g/mL) |
| Solubility (25°C) | DMSO: 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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