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Dihydroethidium

Cat. No. M9696

All AbMole products are for research use only, cannot be used for human consumption.

Dihydroethidium Structure
Synonym:

Hydroethidine; PD-MY 003; DHE

Size Price Availability Quantity
1mg USD 25  USD25 In stock
5mg USD 30  USD30 In stock
10mg USD 60  USD60 In stock
25mg USD 100  USD100 In stock
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Quality Control & Documentation
Biological Activity

Dihydroethidium (also known as Hydroethidine and PD-MY 003) is a cell-permeable blue fluorescent dye. DHE-derived fluorescence at 570 nm is a convenient method for detection of intracellular and extracellular superoxide produced by phagocytic and vascular NADPH oxidase. Dihydroethidium is neuroprotective by reducing superoxide in mice after stroke.

Product Citations
Chemical Information
Molecular Weight 315.41
Formula C21H21N3
CAS Number 104821-25-2
Solubility (25°C) DMSO ≥ 45 mg/mL
Storage 2-8°C, protect from light, dry, sealed
References

[1] Qilong Wang, et al. Methods Mol Biol . Measurement of Reactive Oxygen Species (ROS) and Mitochondrial ROS in AMPK Knockout Mice Blood Vessels

[2] Radoslaw Michalski, et al. Free Radic Biol Med. On the use of fluorescence lifetime imaging and dihydroethidium to detect superoxide in intact animals and ex vivo tissues: a reassessment

[3] Jacek Zielonka, et al. J Biol Chem. Global profiling of reactive oxygen and nitrogen species in biological systems: high-throughput real-time analyses

[4] Francisco R M Laurindo, et al. Methods Enzymol. Assessment of superoxide production and NADPH oxidase activity by HPLC analysis of dihydroethidium oxidation products

[5] L Burnaugh, et al. Theriogenology. Generation of superoxide anion by equine spermatozoa as detected by dihydroethidium

[6] Fengshan Yu, et al. Brain Res. Treatment with dihydroethidium reduces infarct size after transient focal cerebral ischemia in mice

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Keywords: Dihydroethidium, Hydroethidine; PD-MY 003; DHE supplier, Fluorescent Dye, inhibitors, activators

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