Free shipping on all orders over $ 500

Didox

Cat. No. M8770

All AbMole products are for research use only, cannot be used for human consumption.

Didox Structure
Synonym:

N,3,4-Trihydroxybenzamide

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Didox is a ribonucleotide reductase (RNR) inhibitor that inhibits proliferation of and decreased secretion of cytokines IL-6, IFN-g, TNF-a, IL-2, IL-13, IL-10 and IL-4. Didox inhibits proliferation of tamoxifen-resistant breast cancer cells. Didox is an antioxidant that potentiates the cytotoxic profile of doxorubicin.

Chemical Information
Molecular Weight 169.13
Formula C7H7NO4
CAS Number 69839-83-4
Solubility (25°C) DMSO: 2 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Juliete A F Silva, et al. Didox (3,4-dihydroxybenzohydroxamic acid) reduces the vascular inflammation induced by acute intravascular hemolysis

[2] Michela Asperti, et al. The Antitumor Didox Acts as an Iron Chelator in Hepatocellular Carcinoma Cells

[3] Jamie Josephine Avila McLeod, et al. Didox (3,4-dihydroxybenzohydroxamic acid) suppresses IgE-mediated mast cell activation through attenuation of NFκB and AP-1 transcription

[4] Heather L Caslin, et al. Didox (3,4-dihydroxybenzohydroxamic acid) suppresses IL-33-induced cytokine production in primary mouse mast cells

[5] Ahmed M Al-Abd, et al. Didox potentiates the cytotoxic profile of doxorubicin and protects from its cardiotoxicity

Related Products
2-Deoxy-2-fluoro-D-glucose

2-Deoxy-2-fluoro-D-glucose is a radiolabeled glucose analog, which is commonly used in medical imaging techniques such as positron emission tomography (PET) scans.

2-Bromo-4-chlorophenylacetic acid

2-Bromo-4-chlorophenylacetic acid is a biochemical reagent.

CPN-351 TFA

CPN-351 TFA is a selective pentapeptide antagonist of human NMUR1 with a pA2 of 7.35. CPN-351 TFA can be used for the research of inflammation.

5-Phenyluracil

5-Phenyluracil is a pyrimidine derivative, a class of heterocyclic aromatic organic compounds crucial in biochemistry. It serves as a synthetic nucleoside analogue, meaning it mimics the structure of naturally occurring nucleosides like uridine. This structural similarity allows it to participate in biochemical reactions, often interfering with normal cellular processes, making it a valuable tool in studying nucleic acid metabolism and developing antiviral and anticancer agents.

7-Deoxyloganin

7-Deoxyloganin is a biosynthetic precursor of Loganin. 7-Deoxyloganin undergoes hydroxylation catalyzed by 7-deoxyloganin 7-hydroxylase, a cytochrome P450-dependent monooxygenase, to produce Loganin.

  Catalog
Abmole Inhibitor Catalog




Keywords: Didox, N,3,4-Trihydroxybenzamide supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.