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DCAP

Cat. No. M8378

All AbMole products are for research use only, cannot be used for human consumption.

DCAP Structure

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Quality Control & Documentation
Biological Activity

DCAP is a potent broad-spectrum antibiotic that specifically targets the membranes of both Gram-positive and Gram-negative bacteria. It reduces the transmembrane potential, kills stationary-phase cells and sterilizes bacterial biofilms. DCAP has no effect on red blood cell membranes at levels toxic to bacteria.

Chemical Information
Molecular Weight 413.29
Formula C19H22Cl2N2O4
CAS Number 500015-20-3
Solubility (25°C) DMSO: 5 mg/mL (warmed)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Zeinab Raoufi, et al. DcaP porin and its epitope-based subunit promise effective vaccines against Acinetobacter baumannii; in-silico and in-vivo approaches

[2] Zeinab Breijyeh, et al. Resistance of Gram-Negative Bacteria to Current Antibacterial Agents and Approaches to Resolve It

[3] Katherine A Hurley, et al. Membrane-Targeting DCAP Analogues with Broad-Spectrum Antibiotic Activity against Pathogenic Bacteria

[4] Andrew T Schuster, et al. Condensin II subunit dCAP-D3 restricts retrotransposon mobilization in Drosophila somatic cells

[5] Ye-Jin Eun, et al. DCAP: a broad-spectrum antibiotic that targets the cytoplasmic membrane of bacteria

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Keywords: DCAP supplier, inhibitors, activators

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