Cytidine-5'-monophospho-N-acetylneuraminic acid is a nucleotide.
|Solubility (25°C)||Soluble in water|
|Storage||-20°C, dry, sealed|
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
|Avidin (from egg white)
Avidin is homotetrameric protein (68kDa) that is obtained from egg whites. Avidin forms an extremely strong complex with d-biotin (Kd ~ 10-15). This activity has made both avidin and biotin extremely useful labels in immunochemical methods of detection and quantitation.
Elotuzumab is a First-in-Class monoclonal antibody directed against the SLAMF7 receptor, it specifically binds to signaling lymphocyte activating molecule family member 7 (SLAMF7) and activates the body's immune response to attack and kill multiple myeloma cells. Elotuzumab exerts its anti-myeloma effects mainly through ADCC and activation of NK cells.
|TRITC-dextran (70 kDa)
TRITC-dextran (70 kDa) is a fluorescent derivative of a dextran fraction with an average molecular weight of approximately 70000. TRITC dextrans are prepared from special dextran fractions by coupling to tetramethylrhodamine B isothiocyanate (mixed isomers).
Insulin glargine is a long-acting insulin analog. Insulin glargine can be used for the research of diabetes mellitus.
Insulin aspart (B28Asp) is a fast-acting analog of human insulin. Insulin aspart can be used for researching diabetes.
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