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Cycloastragenol

Cat. No. M11526

All AbMole products are for research use only, cannot be used for human consumption.

Cycloastragenol Structure
Synonym:

Astramembrangenin; Cyclosieversigenin

Size Price Availability Quantity
1mg USD 25  USD25 In stock
5mg USD 45  USD45 In stock
10mg USD 70  USD70 In stock
25mg USD 90  USD90 In stock
50mg USD 135  USD135 In stock
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Quality Control & Documentation
Biological Activity

Cycloastragenol (Astramembrangenin) is the active form of Astragaloside IV and has antioxidant, anti-inflammatory, anti-aging, anti-apoptotic and cardiovascular protective effects. Cycloastragenol is an effective telomerase activator that lengthens telomeres. Cycloastragenol alleviates age-related bone loss and improves bone microstructure and biomechanical properties.

Chemical Information
Molecular Weight 490.71
Formula C30H50O5
CAS Number 78574-94-4
Form Solid
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Muhammad Ikram, et al. Cells. Cycloastragenol, a Triterpenoid Saponin, Regulates Oxidative Stress, Neurotrophic Dysfunctions, Neuroinflammation and Apoptotic Cell Death in Neurodegenerative Conditions

[2] Jiahuan Wu, et al. Phytother Res. Cycloastragenol protects against glucocorticoid-induced osteogenic differentiation inhibition by activating telomerase

[3] Man Li, et al. Acta Pharmacol Sin. Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia

[4] Chen Chen, et al. Nat Prod Res. Anti-aging derivatives of cycloastragenol produced by biotransformation

[5] Yongjie Yu, et al. Exp Ther Med. Cycloastragenol: An exciting novel candidate for age-associated diseases

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Keywords: Cycloastragenol, Astramembrangenin; Cyclosieversigenin supplier, Telomerase, inhibitors, activators

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