All AbMole products are for research use only, cannot be used for human consumption.
Cyclo (-RGDfK) is an effective and specific αvβ3 integrin inhibitor. Cyclo (-RGDfK) has a high affinity for purified integrin (Kd = 41.70 nM). In athymic mice bearing α(v)β(3)-integrin-positive C6 gliomas, Cyclo (-RGDfK) modification induces less tumor metabolic activity, less tumor progression, fewer intratumoral vessels.
| Molecular Weight | 603.67 |
| Formula | C27H41N9O7 |
| CAS Number | 161552-03-0 |
| Solubility (25°C) | Water 60 mg/mL DMSO 70 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Integrin Products |
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| Volociximab
Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 (EC50=0.2 nM). Volociximab has antiangiogenic and antitumor activities and inhibits the proliferation of human umbilical vein vascular endothelial cells (HUVECs). |
| GSK 3008348 hydrochloride
GSK 3008348 hydrochloride is a small molecule integrin αvβ6 antagonist. |
| HSDVHK-NH2
HSDVHK-NH2 is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC50 of 1.74 pg/mL (2.414 pM). |
| LDV
LDV, a tripeptide, is a non-fluorescent analog of LDV-FITC. |
| Cyclo(RADfK)
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis. |
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Products are for research use only. Not for human use. We do not sell to patients.
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