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CS-6253 is an agonist for ATP-binding cassette 1 (ABCA 1). CS-6253 improves the amyloid-β42/40 ratio, and affects lipoprotein metabolism in plasma. CS-6253 generates cholesterol-rich high-density lipoprotein (HDL) particles, and induces the release of microparticles.
Sequence: Glu-Val-{Cit}-Ser-Lys-Leu-Glu-Glu-Trp-Leu-Ala-Ala-Leu-{Cit}-Glu-Leu-Ala-Glu-Glu-Leu-Leu-Ala-Arg-Leu-Lys-Ser
| Molecular Weight | 3055.48 |
| Formula | C136H228N36O43 |
| CAS Number | 1627911-44-7 |
| Solubility (25°C) | Water 10 mg/mL (May need adjust pH to 10 with NaOH) |
| Storage | -20°C, dry, sealed |
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