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CPI-0610 is a small molecule inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, with potential antineoplastic activity. The BET inhibitor CPI-0610 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histone peptides.
| Molecular Weight | 365.81 |
| Formula | C20H16ClN3O2 |
| CAS Number | 1380087-89-7 |
| Solubility (25°C) | 73 mg/mL in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Douglas Tremblay, et al. Next Generation Therapeutics for the Treatment of Myelofibrosis
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