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Coixol

Cat. No. M9551

All AbMole products are for research use only, cannot be used for human consumption.

Coixol Structure
Synonym:

6-Methoxy-2-benzoxazolinone; MBOA

Size Price Availability Quantity
5mg USD 60  USD60 In stock
10mg USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

Coixol is a natural product extracted from Coix Lachryma-Jobi var. ma-yuen. Coixol inhibited the expression of MUC5AC mucin gene and production of MUC5AC mucin protein, induced by EGF or TNF-α from NCI-H292 cells. Coixol decreased PMA-induced MUC5AC mucin secretion from NCI-H292 cells.

Chemical Information
Molecular Weight 165.15
Formula C8H7NO3
CAS Number 532-91-2
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yusheng Hu, et al. Coixol Suppresses NF-κB, MAPK Pathways and NLRP3 Inflammasome Activation in Lipopolysaccharide-Induced RAW 264.7 Cells

[2] Abdul Hameed, et al. Coixol amplifies glucose-stimulated insulin secretion via cAMP mediated signaling pathway

[3] Hwa Yeon Kim, et al. Endoplasmic reticulum stress induced by an ethanol extract of Coicis semen in Chang liver cells

[4] Arslan Ali, et al. Sensitive quantification of coixol, a potent insulin secretagogue, in Scoparia dulcis extract using high-performance liquid chromatography combined with tandem mass spectrometry and UV detection

[5] Hyun Jae Lee, et al. Suppressive effects of coixol, glyceryl trilinoleate and natural products derived from Coix Lachryma-Jobi var. ma-yuen on gene expression, production and secretion of airway MUC5AC mucin

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Keywords: Coixol, 6-Methoxy-2-benzoxazolinone; MBOA supplier, Plant growth regulators, inhibitors, activators

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