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CMFDA

Cat. No. M21548
CMFDA Structure
Size Price Availability Quantity
1mg USD 300  USD300 In stock
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Quality Control & Documentation
Biological Activity

CMFDA is a cell-permeable fluorescent probe that can be used as a cellular tracer. CMFDA can be cleaved by non-specific esterases common to living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope.

Chemical Information
Molecular Weight 464.85
Formula C25H17ClO7
CAS Number 136832-63-8
Solubility (25°C) N/A
Storage -20°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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5-CFDA

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5(6)-FAM SE

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5-FAM SE

5-FAM SE is a green fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates.

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Keywords: CMFDA supplier, Fluorescent Dye, inhibitors, activators

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