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cis-Zeatin riboside

Cat. No. M31089
cis-Zeatin riboside Structure
Synonym:

cZR

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Biological Activity

cis-Zeatin riboside is a natural product found in alfalfa that has cytokinin effects.

Chemical Information
Molecular Weight 351.36
Formula C15H21N5O5
CAS Number 15896-46-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Toru Kudo, et al. Plant Physiol. Cytokinin activity of cis-zeatin and phenotypic alterations induced by overexpression of putative cis-Zeatin-O-glucosyltransferase in rice

[2] C S Mauk, et al. Plant Physiol. Physiology of Tuberization in Solanum tuberosum L: cis-Zeatin Riboside in the Potato Plant: Its Identification and Changes in Endogenous Levels as Influenced by Temperature and Photoperiod

[3] Yeonjin K Veach, et al. Plant Physiol. O-glucosylation of cis-zeatin in maize. Characterization of genes, enzymes, and endogenous cytokinins

[4] N. V. Bassil, et al. Plant Physiol. Partial Purification of a cis-trans-Isomerase of Zeatin from Immature Seed of Phaseolus vulgaris L

[5] G M Banowetz. Hybridoma. Monoclonal antibodies against the plant cytokinin, cis-zeatin riboside

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Keywords: cis-Zeatin riboside, cZR supplier, Plant growth regulators, inhibitors, activators


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