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Cinromide is an inhibitor of epithelial neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 0.5 μM. Cinromide (10-100 μM) inhibits 5-HT-induced contractions in rat fundus strips by 46%.
| Molecular Weight | 254.12 |
| Formula | C11H12BrNO |
| CAS Number | 58473-74-8 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] P Chiu, et al. Neuropharmacology. The effect of cinromide on "kindled" seizures in the rat
[3] A J Wilensky, et al. Epilepsia. Cinromide in epilepsy: a pilot study
[4] G H Fromm, et al. Epilepsia. Effect of cinromide on inhibitory and excitatory mechanisms
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