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Cinnabarinic acid

Cat. No. M6607

All AbMole products are for research use only, cannot be used for human consumption.

Cinnabarinic acid Structure

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Quality Control & Documentation
Biological Activity

Cinnabarinic acid is a mGlu4 receptor agonist. Activates mGlu4 receptors in transiently transfected HEK293 cells; selective over all other mGlu subtypes (mGlu1, mGlu2 and mGlu5-8). Decreases cAMP levels in native cultured cerebellar granule cells. Also counteracts excitotoxic neuronal cell death induced by NMDA in mixed cultures of cortical cells; displays neuroprotective activity.

Chemical Information
Molecular Weight 300.22
Formula C14H8N2O6
CAS Number 606-59-7
Solubility (25°C) DMSO 30.02 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Zhang, et al. Mol Cancer Ther. The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.

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Keywords: Cinnabarinic acid supplier, inhibitors, activators

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