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CH7233163

Cat. No. M40642

All AbMole products are for research use only, cannot be used for human consumption.

CH7233163 Structure

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Quality Control & Documentation
Biological Activity

CH7233163 is a non-covalent ATP-competitive EGFR- del19 /T790M/C797S inhibitor that can achieve potent inhibitory activity and mutation selection by exploiting multiple interactions with the αC helix conformation of EGFR, with antitumor activity, and can be used in studies related to non-small cell lung cancer (NSCLC).

Chemical Information
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ravi Saini et al. Sci Rep. Discovery of the allosteric inhibitor from actinomyces metabolites to target EGFRCSTMLR mutant protein: molecular modeling and free energy approach

[2] Kenji Kashima et al. Mol Cancer Ther. CH7233163 Overcomes Osimertinib-Resistant EGFR-Del19/T790M/C797S Mutation

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CH7233163 

CH7233163 is a noncovalent ATP-competitive inhibitor for EGFR-Del19/T790M/C797S.

  Catalog
Abmole Inhibitor Catalog




Keywords: CH7233163 supplier, EGFR/HER2, inhibitors, activators

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