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Carboxyfluorescein succinimidyl ester (CFSE) is a fluorescent cell staining dye. CFSE is cell permeable and covalently couples, via its succinimidyl group, to intracellular molecules, notably, to intracellular lysine residues and other amine sources. The binding of CFDA-SE fluorescent dye to cells is stable. It is not toxic and does not modify the viability of labeled cells. CFDA-SE fluorescent dye is a suitable fluorochrome for cell labeling. CFDA-SE persists in cells 24 h after labeling, allowing the long-term detection of labeled cells.
In vivo labeling of cells with CFSE is feasible with virtually no toxic effect on the labeled or adjacent cells. It has advantages in relatively long-term migration studies as demonstrated by the recovery of T-cells in the peripheral lymphoid organs.
Another CAS#: 150206-15-8
ACS Nano. 2025 Jun 18;19(25):22968-22987.
Biomimetic Ginsenoside Rb1 and Probucol Co-Assembled Nanoparticles for Targeted Atherosclerosis Therapy via Inhibition of Oxidative Stress, Inflammation, and …
CFDA-SE purchased from AbMole
Adv Sci (Weinh). 2025 Mar 08; .
Osteosarcoma Cell-Derived Migrasomes Promote Macrophage M2 Polarization to Aggravate Osteosarcoma Proliferation and Metastasis
CFDA-SE purchased from AbMole
EMBO Mol Med. 2024 Mar 6;024-00051.
The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor
CFDA-SE purchased from AbMole
Neural Regen Res. 2024 May;19(5):1142-1149.
Bromocriptine protects perilesional spinal cord neurons from lipotoxicity after spinal cord injury
CFDA-SE purchased from AbMole
Antibiotics (Basel). 2024 Jun 3;13(6):521.
Antifungal Activity, Synergism with Fluconazole or Amphotericin B and Potential Mechanism of Direct Current against Candida albicans Biofilms and Persisters
CFDA-SE purchased from AbMole
Cancer Lett. 2023 Jun 22;216278.
Rapid generation of CD19 CAR-T cells by minicircle DNA enables anti-tumor activity and prevents fatal CAR-B leukemia
CFDA-SE purchased from AbMole
Cancer Lett. 2023 Aug 1;568:216278.
Rapid generation of CD19 CAR-T Cells by minicircle DNA enables anti-tumor activity and prevents fatal CAR-B leukemia
CFDA-SE purchased from AbMole
Immunology. 2023 May 19.
EPOR activation attenuates colitis via enhancing LC3B‐dependent apoptotic cell clearance
CFDA-SE purchased from AbMole
J Nanobiotechnology. 2022 Aug 2;20(1):356.
Lactobacillus cell envelope-coated nanoparticles for antibiotic delivery against cariogenic biofilm and dental caries
CFDA-SE purchased from AbMole
Laboratory Investigation. 2022 Jul 21.
The N6-methyladenosine writer WTAP contributes to the induction of immune tolerance post kidney transplantation by targeting regulatory T cells
CFDA-SE purchased from AbMole
| Molecular Weight | 557.46 |
| Formula | C29H19NO11 |
| CAS Number | 150347-59-4 |
| Solubility (25°C) | DMSO 80 mg/mL |
| Storage | 4°C, protect from light |
[8] Graziano M, et al. Exp Cell Res. The fate of thymocytes labeled in vivo with CFSE.
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