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Cerivastatin is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally active HMG-CoA reductase inhibitor, with a Ki of 1.3 nM/L. Cerivastatin reduces low-density lipoprotein cholesterol levels. Cerivastatin also inhibits proliferation and invasiveness of MDA-MB-231 cells, mainly by RhoA inhibition, and has anti-cancer effect.
| Molecular Weight | 459.55 |
| Formula | C26H34FNO5 |
| CAS Number | 145599-86-6 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] Stephen P Adams, et al. Cochrane Database Syst Rev. Cerivastatin for lowering lipids
| Related HMG-CoA Reductase Products |
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(3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. |
| Fluvastatin
Fluvastatin is the first fully synthesized, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin protects vascular smooth muscle cells from oxidative stress through an Nrf2-dependent antioxidant pathway. |
| Pravastatin lactone
Pravastatin lactone is a potent HMG-CoA inhibitor. |
| HMG-CoA Reductase-IN-1
HMG-CoA Reductase-IN-1 is a HMG-CoA reductase inhibitor. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
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