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CellTracker CM-DiI

Cat. No. M45079
CellTracker CM-DiI Structure


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Biological Activity

CellTracker CM-DiI is a lipophilic fluorochrome that can be used to visualize the migration of lymphocytes.CellTracker CM-DiI can detect labeled cells on tissue sections, Ex: 553 nm; Em: 570 nm.

Chemical Information
Molecular Weight 1051.49
Formula C68H105Cl2N3O
CAS Number 180854-97-1
Form Solid
Storage -20°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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Keywords: CellTracker CM-DiI, CM-DiI supplier, Fluorescent Dye, inhibitors, activators

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