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CD161

Cat. No. M28718

All AbMole products are for research use only, cannot be used for human consumption.

CD161 Structure
Synonym:

NKR-P1A

Price and Availability

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Quality Control & Documentation
Biological Activity

CD161 (NKR-P1A) is a potent, selective and orally bioavailable bromodomain and extra-terminal (BET) bromodomain inhibitor with an IC50s of 28.2 nM and 7.2 nM for BRD4 BD1 and BRD4 BD2, respectively. CD161 has good anticancer activity.

Chemical Information
Molecular Weight 435.48
Formula C26H21N5O2
CAS Number 1627716-22-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Veronique M Braud, et al. Front Immunol. LLT1-CD161 Interaction in Cancer: Promises and Challenges

[2] Wang Di, et al. Cancer Sci. Clinical characterization and immunosuppressive regulation of CD161 (KLRB1) in glioma through 916 samples

[3] Xiaohan Zhou, et al. Front Immunol. A Pan-Cancer Analysis of CD161, a Potential New Immune Checkpoint

[4] Vanaja Konduri, et al. Front Immunol. CD8+CD161+ T-Cells: Cytotoxic Memory Cells With High Therapeutic Potential

[5] Nathan D Mathewson, et al. Cell. Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis

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  Catalog
Abmole Inhibitor Catalog




Keywords: CD161, NKR-P1A supplier, Epigenetic Reader Domain, inhibitors, activators

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