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Carrageenan

Cat. No. M40793
Carrageenan Structure
Size Price Availability Quantity
10g USD 30  USD30 In stock
25g USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Carrageenan is a biochemical reagent that can be used to construct animal models of chronic non-bacterial prostatitis, models of synovitis, and models of prostatitis.

Chemical Information
CAS Number 9000-07-1
Form Solid
Storage 4°C, protect from light
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Barbara Borsani et al. Nutrients. The Role of Carrageenan in Inflammatory Bowel Diseases and Allergic Reactions: Where Do We Stand?

[2] Zhiwei Liu et al. Molecules. Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds

[3] Błażej B Błaszak et al. Acta Sci Pol Technol Aliment. Carrageenan as a functional additive in the production of cheese and cheese-like products

[4] Vipul D Prajapati et al. Carbohydr Polym. Carrageenan: a natural seaweed polysaccharide and its applications

[5] Liang Li et al. Carbohydr Polym. Carrageenan and its applications in drug delivery

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