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Calcium dobesilate

Cat. No. M20436

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Calcium dobesilate Structure
Synonym:

calcium dihydroxy-2,5-benzenesulfonate

Size Price Availability Quantity
500mg USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Calcium dobesilate is a vascular protector with oral activity that can clear hydroxyl free radicals, with an IC50 of 1.1 pM. Calcium dobesilate has antioxidant activity and helps to reduce oxidative stress and inflammation in the retinas of diabetic mice.

Chemical Information
Molecular Weight 418.41
Formula C12H10CaO10S2
CAS Number 20123-80-2
Solubility (25°C) DMSO 90 mg/mL
Water ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yue Wang, et al. Front Pharmacol. Calcium Dobesilate Restores Autophagy by Inhibiting the VEGF/PI3K/AKT/mTOR Signaling Pathway

[2] Jie Liu, et al. Life Sci. Calcium Dobesilate and Micro-vascular diseases

[3] XinYuan Zhang, et al. Sci China Life Sci. Calcium dobesilate for diabetic retinopathy: a systematic review and meta-analysis

[4] Agustn Ciapponi, et al. Angiology. Calcium dobesilate for chronic venous insufficiency: a systematic review

[5] H Reuter. Z Allgemeinmed. [Calcium dobesilate]

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Keywords: Calcium dobesilate, calcium dihydroxy-2,5-benzenesulfonate supplier, inhibitors, activators

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