Free shipping on all orders over $ 500

Calcium dobesilate

Cat. No. M20436

All AbMole products are for research use only, cannot be used for human consumption.

Calcium dobesilate Structure
Synonym:

calcium dihydroxy-2,5-benzenesulfonate

Size Price Availability Quantity
500mg USD 50  USD50 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Calcium dobesilate is a vascular protector with oral activity that can clear hydroxyl free radicals, with an IC50 of 1.1 pM. Calcium dobesilate has antioxidant activity and helps to reduce oxidative stress and inflammation in the retinas of diabetic mice.

Chemical Information
Molecular Weight 418.41
Formula C12H10CaO10S2
CAS Number 20123-80-2
Solubility (25°C) DMSO 90 mg/mL
Water ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yue Wang, et al. Front Pharmacol. Calcium Dobesilate Restores Autophagy by Inhibiting the VEGF/PI3K/AKT/mTOR Signaling Pathway

[2] Jie Liu, et al. Life Sci. Calcium Dobesilate and Micro-vascular diseases

[3] XinYuan Zhang, et al. Sci China Life Sci. Calcium dobesilate for diabetic retinopathy: a systematic review and meta-analysis

[4] Agustn Ciapponi, et al. Angiology. Calcium dobesilate for chronic venous insufficiency: a systematic review

[5] H Reuter. Z Allgemeinmed. [Calcium dobesilate]

Related Products
PCL-PEG-MAL

PCL-PEG-MAL is an amphiphilic block copolymer consisting of polycaprolactone (PCL), polyethylene glycol (PEG) and maleimide (MAL) functional groups. PCL-PEG-MAL is used in targeted delivery systems, surface modification of nanomaterials, functionalisation of biomaterials and biosensing technologies for specific chemical linkages or biomolecular immobilisation.

DSPE-PEG-Streptavidin

DSPE-PEG-Streptavidin is an important biocoupling molecule widely used in biomedical research, especially in drug delivery, targeted therapies, immunodiagnostics and biosensors. Through the specific binding between streptavidin and biotin, DSPE-PEG-Streptavidin can help to achieve efficient loading and targeted action in targeted delivery systems. In addition, the molecule is widely used in molecular imaging and bioassays, especially for molecular recognition using the strong affinity between streptavidin and biotin in assay platforms that require high sensitivity and specificity.

E7107

E7107 is a first-in-class precursor messenger ribonucleic acid (pre-mRNA) spliceosome inhibitor.

KL044

KL044 is a stabilizer of the clock protein cryptochrome (CRY). KL044 is a potent chemical probe with a pEC50 value of 7.32, leading to the extension of the circadian period and repression of Per2 activity.

2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide

2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide is a biochemical material that can be used in scientific research.

  Catalog
Abmole Inhibitor Catalog




Keywords: Calcium dobesilate, calcium dihydroxy-2,5-benzenesulfonate supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.