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Calcein

Cat. No. M9870
Calcein Structure
Synonym:

Fluorexon

Size Price Availability Quantity
100mg USD 30  USD30 In stock
1g USD 50  USD50 In stock
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Quality Control
  • Current batch:
  • Purity AR
  • COA
  • MSDS
Biological Activity

Calcein is a fluorescent dye and self-quenching probe, used as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 622.53
Formula C30H26N2O13
CAS Number 1461-15-0
Purity AR
Solubility DMSO 80 mg/mL
Storage 2-8°C, protect from light, dry, sealed
References

[1] Luis Fernando Marques-Santos, et al. Fish Shellfish Immunol. ABCB1 and ABCC1-like transporters in immune system cells from sea urchins Echinometra lucunter and Echinus esculentus and oysters Crassostrea gasar and Crassostrea gigas

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Calcein, Fluorexon supplier, Fluorescent Dye, inhibitors

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