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Buparlisib Hydrochloride (BKM120 Hydrochloride) is a pan-class I PI3K inhibitor, with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively.
| Molecular Weight | 446.85 |
| CAS Number | 1312445-63-8 |
| Solubility (25°C) | DMSO ≥ 50 mg/mL |
| Storage | 2-8°C, dry, sealed |
[2] Brinda Alagesan, et al. Combined MEK and PI3K inhibition in a mouse model of pancreatic cancer
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| RV-1729
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