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Bromodomain IN-2

Cat. No. M41642

All AbMole products are for research use only, cannot be used for human consumption.

Bromodomain IN-2 Structure

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Quality Control & Documentation
Biological Activity

BD-IN-1 is a pan bromodomain (BD) inhibitor with KD values of 250, 420, 130, 430, 67, 240, 970 nM for BRD4(1), CBP, BRPF1B, BRD7, BRD9, BRDT(1), CECR2 respectively.

Chemical Information
Molecular Weight 288.77
Formula C16H17ClN2O
CAS Number 2445335-77-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tiziana Servidei et al. Int J Mol Sci. The BET Inhibitor OTX015 Exhibits In Vitro and In Vivo Antitumor Activity in Pediatric Ependymoma Stem Cell Models

[2] Todd M Stevens et al. Mod Pathol. NUTM1-rearranged neoplasia: a multi-institution experience yields novel fusion partners and expands the histologic spectrum

[3] Minsun Jung et al. Oncologist. Clinicopathological and Preclinical Findings of NUT Carcinoma: A Multicenter Study

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BBC0403 

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  Catalog
Abmole Inhibitor Catalog




Keywords: Bromodomain IN-2 supplier, Epigenetic Reader Domain, inhibitors, activators

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