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Briciclib

Cat. No. M20585

All AbMole products are for research use only, cannot be used for human consumption.

Briciclib Structure
Synonym:

ON-014185

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Quality Control & Documentation
Biological Activity

Briciclib is a water soluble derivative of ON-013100, a small molecule that binds to and inhibits eukaryotic translation initiation factor 4E (eIF4E) .

Chemical Information
Molecular Weight 474.42
Formula C19H23O10PS
CAS Number 865783-99-9
Solubility (25°C) DMSO 95 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Khaled M Elattar, et al. Curr Org Synth. Bicyclic 5-6 Systems: Comprehensive Synthetic Strategies for the Annulations of Pyrazolo[ 1,5-a]pyrimidines

[2] Shahrzad Ahangarzadeh, et al. Drug Discov Today. Bicyclic peptides: types, synthesis and applications

[3] Elena Lenci, et al. Org Biomol Chem. Bicyclic acetals: biological relevance, scaffold analysis, and applications in diversity-oriented synthesis

[4] Curran A Rhodes, et al. Chemistry. Bicyclic Peptides as Next-Generation Therapeutics

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  Catalog
Abmole Inhibitor Catalog




Keywords: Briciclib, ON-014185 supplier, inhibitors, activators

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