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Bohemine

Cat. No. M6160

All AbMole products are for research use only, cannot be used for human consumption.

Bohemine Structure
Size Price Availability Quantity
5mg USD 58  USD58 In stock
10mg USD 85  USD85 In stock
25mg USD 150  USD150 In stock
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Quality Control & Documentation
Biological Activity

Bohemine is A selective CDK inhibitor with IC50 of 4.6 μM, 83 μM and 2.7 μM against Cdk2/ Cyclin E, Cdk2/ Cyclin A and Cdk9/cyclin T1, respectively. Bohemine also inhibited ERK2, IC50 was 52 μM, and inhibited CDK1, CDK4 and CDK6. Bohemine is also a purine analogue and has a wide range of anticancer activities.

Protocol (for reference only)
Cell Experiment
Cell lines
Preparation method
Concentrations
Incubation time
Animal Experiment
Animal models
Formulation
Dosages
Administration
Chemical Information
Molecular Weight 340.42
Formula C18H24N6O
CAS Number 189232-42-6
Form Solid
Solubility (25°C) DMSO 80 mg/mL
Storage Powder -20°C
References

[1] Franek F, et al. Cytotechnology. Diverse effects of the cyclin-dependent kinase inhibitor bohemine: Concentration- and time-dependent suppression or stimulation of hybridoma culture

[2] Chmela Z, et al. Drug Metab Dispos. In vivo metabolism of 2,6,9-trisubstituted purine-derived cyclin-dependent kinase inhibitor bohemine in mice: glucosidation as the principal metabolic route.

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  Catalog
Abmole Inhibitor Catalog




Keywords: Bohemine supplier, CDK, inhibitors, activators

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