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BMS-823778

Cat. No. M7671

All AbMole products are for research use only, cannot be used for human consumption.

BMS-823778 Structure

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Quality Control & Documentation
Biological Activity

BMS-823778 is an orally available potent and selective inhibitor of 11-β-hydroxysteroid-dehydrogenase 1 (11βHSD-1). BMS-823778 is an antihyperglycaemic.

Chemical Information
Molecular Weight 364.27
Formula C18H18ClN3O · HCl
CAS Number 1140898-87-8
Solubility (25°C) DMSO: 5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jiachang Gong, et al. Physiologically-based pharmacokinetic modelling of a CYP2C19 substrate, BMS-823778, utilizing pharmacogenetic data

[2] Jiachang Gong, et al. Clinical Pharmacokinetics and the Impact of Genetic Polymorphism on a CYP2C19 Substrate, BMS-823778, in Healthy Subjects

[3] Yaofeng Cheng, et al. Clinical significance of CYP2C19 polymorphisms on the metabolism and pharmacokinetics of 11β-hydroxysteroid dehydrogenase type-1 inhibitor BMS-823778

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Keywords: BMS-823778 supplier, Hydroxysteroid dehydrogenase, inhibitors, activators

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