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Blu-945 is a potent inhibitor of selective epidermal growth factor receptor (EGFR). EGFR is a member of the erbB receptor family, which includes receptors for transmembrane protein tyrosine kinases. Blu-945 effectively inhibits EGFR with L858R and/or exon 19 deletion mutations, T790M mutations and C797S mutations. Blu-945 contributes to effective administration and reduces egFR-mediated targeted toxicity. Blu-945 has the potential to study cancer diseases.
Molecular Weight | 556.7 |
Formula | C28H37FN6O3S |
CAS Number | 2660250-10-0 |
Solubility (25°C) | DMSO 90 mg/mL |
Storage | 4°C, protect from light |
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