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BI-685509 

Cat. No. M28623

All AbMole products are for research use only, cannot be used for human consumption.

BI-685509  Structure

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Quality Control & Documentation
Biological Activity

BI-685509 is a potent and orally active sGC activator. BI-685509 restores cyclic guanosine monophosphate (cGMP) and improves functionality of nitric oxide (NO) pathways. BI-685509 can be used in research of chronic kidney disease (CKD) and diabetic kidney disease (DKD).

Chemical Information
Molecular Weight 582.69
Formula C34H38N4O5
CAS Number 1579514-06-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] David Z I Cherney, et al. Diabetes Obes Metab. Safety, tolerability, pharmacodynamics and pharmacokinetics of the soluble guanylyl cyclase activator BI 685509 in patients with diabetic kidney disease: A randomized trial

[2] Amanda K Jones, et al. J Pharmacol Exp Ther. Soluble Guanylyl Cyclase Activator BI 685509 Reduces Portal Hypertension and Portosystemic Shunting in a Rat Thioacetamide-Induced Cirrhosis Model

[3] Glenn A Reinhart, et al. J Pharmacol Exp Ther. The Novel, Clinical-Stage Soluble Guanylate Cyclase Activator BI 685509 Protects from Disease Progression in Models of Renal Injury and Disease

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  Catalog
Abmole Inhibitor Catalog




Keywords: BI-685509  supplier, inhibitors, activators

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