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β-D-Glucose

Cat. No. M39633
β-D-Glucose Structure
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Biological Activity

β-D-Glucose is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Chemical Information
Molecular Weight 180.16
Formula C6H12O6
CAS Number 492-61-5
Form Solid
Solubility (25°C) Water 100 mg/mL (ultrasonic)
Storage 4°C, protect from light, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Yu-Han Jiang et al. Food Nutr Res. In vitro anti-hepatocellular carcinogenesis of 1,2,3,4,6-Penta-O-galloyl-β-D-glucose

[2] K C Wong et al. Acta Crystallogr Sect E Struct Rep Online. catena-Poly[[sodium-di-μ-β-d-glucose] chloride]

[3] Sandip B Bankar et al. Biotechnol Adv. Glucose oxidase--an overview

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Keywords: β-D-Glucose supplier, inhibitors, activators


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