Free shipping on all orders over $ 500
β-casomorphin, bovine (β-Casomorphin-7 (bovine)) acetate is an opioid-active peptide with an IC50 value of 14 μM for binding to opioid receptors.
Sequence：Tyr-Pro-Phe-Pro-Gly-Pro-Ile.
| Molecular Weight | 849.97 |
| Formula | C43H59N7O11 |
| CAS Number | 72122-62-4 (free base) |
| Solubility (25°C) | DMSO 50 mg/mL Water 25 mg/mL |
| Storage | -20°C, protect from light, dry, sealed |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Opioid Receptor Products |
|---|
| Nalfurafine (TRK-820)
Nalfurafine is an effective and selective agonist of G protein-biased κ-opioid receptor with high translational potential. |
| Bevenopran
Bevenopran (CB-5945) is a peripheral μ-opioid receptor antagonist. |
| LY2795050
LY2795050 is a short-acting selective κ(kappa)-opioid receptor (KOR) antagonist. LY2795050 has high affinity for the KOR with Ki value of 0.72 nM. LY2795050 can be used for the research of central nervous system dysfunction. |
| BTRX-335140
BTRX-335140 is a selective and orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. Navacaprant endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats. |
| GSK1521498
GSK1521498 is a novel, potent and selective μ-opioid receptor antagonist. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.
