All AbMole products are for research use only, cannot be used for human consumption.
BAY-1816032 is a potent and oral available BUB1 (budding uninhibited by benzimidazoles 1) kinase inhibitor with an IC50 of 7 nM. BAY-1816032 abrogates nocodazole-induced Thr-120 phosphorylation of the major BUB1 target protein histone H2A in HeLa cells with an IC50 of 29 nM, induced lagging chromosomes and mitotic delay. BAY 1816032 showed long target residence time and induced chromosome mis-segregation upon combination with low concentrations of paclitaxel.
| Molecular Weight | 534.51 |
| Formula | C27H24F2N6O4 |
| CAS Number | 1891087-61-8 |
| Solubility (25°C) | DMSO ≥ 17 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Products |
|---|
| D-Allulose
D-Allulose (D-Psicose) is an ultralow-energy monosaccharide sugar. It is a C-3 epimer of D-fructose, and is present in small quantities in agricultural products and commercially-prepared carbohydrate complexes. |
| N,N-Dimethyltrifluoromethanesulfonamide
N,N-Dimethyltrifluoromethanesulfonamide (DMTMSA) is a trifluoromethanesulfonamide solvent. |
| Lucicebtide
Lucicebtide is a peptide antagonist of the transcription factor C/EBPβ, a key activator of the transcriptional program in immunosuppressive macrophages. Lucicebtide shows highly potent inhibition against C/EBPB-ATF5 association with IC50 of 24.6 nM in a competitive ELISA assay. |
| Eloralintide
Eloralintide (LY 3841136) is an AMYR agonist. |
| Gadoteric acid
Gadoteric acid is a macrocyclic, paramagnetic, gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI) of the brain, spine, and related tissues. Gadoteric acid is able to detect and visualize areas of blood-brain barrier disruption and abnormal vascular distribution. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
