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Azophloxine

Cat. No. M10338
Azophloxine Structure
Synonym:

Acid Red 1

Size Price Availability Quantity
10g USD 30  USD30 In stock
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Quality Control
  • Current batch:
  • Purity BS
  • COA
  • MSDS
Biological Activity

Azophloxine, also known as acid red 1 (AR 1), is a member of synthetic red azo dye family. Azo dye is an organic dye with good photo-thermal stability, dissolvability and easy preparation feature. In addition, it also has noticeable third order nonlinearity and good optical power limiting properties. It has been used as a real acid counterstain in light and fluorescence microscopy. Azophloxine also facilitates the determination of proteins and peptides. Azophloxine has been used as a dye in Von Kossa staining and nonlinear optical studies. It is also used in photocatalytic tests.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 509.42
Formula C18H13N3Na2O8S2
CAS Number 3734-67-6
Purity BS
Solubility Water
Storage RT, protect from light, dry, sealed
References

[1] Ayumi Matsumoto, et al. Kidney Int Rep. Quantitative Analyses of Foot Processes, Mitochondria, and Basement Membranes by Structured Illumination Microscopy Using Elastica-Masson- and Periodic-Acid-Schiff-Stained Kidney Sections

[2] Qin Wei, et al. Anal Sci. A highly sensitive and rapid assay for protein determination in human urine and penicillin using a Rayleigh light-scattering technique with benzeneazo-8-acetylamino-1-naphthol-3,6-disulfonic acid sodium salt

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Azophloxine, Acid Red 1 supplier, Fluorescent Dye, inhibitors

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