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ATM Inhibitor-9

Cat. No. M41404

All AbMole products are for research use only, cannot be used for human consumption.

ATM Inhibitor-9 Structure

Price and Availability

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Quality Control & Documentation
Biological Activity

ATM Inhibitor-9 is a potent ATM inhibitor with IC505 nM for ATM kinase, useful in cancer research.

Chemical Information
Molecular Weight 448.56
Formula C25H32N6O2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Dong Wha Jun et al. Oncotarget. DDRI-9: a novel DNA damage response inhibitor that blocks mitotic progression

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KU 59403 is a potent ATM inhibitor, with IC50 values of 3 nM, 9.1 μM and 10 μM for ATM, DNA-PK and PI3K, respectively.

SKLB-197 

SKLB-197 showed an IC50 value of 0.013 μM against ATR but very weak or no activity against other 402 protein kinases.

ATR-IN-4 

ATR-IN-4 is a potent ATR (Ataxia telangiectasia mutated gene Rad 3-associated kinase) inhibitor.

M3541 

M3541 is a potent, ATP-competitive and selective ATM inhibitor with an IC50 of 0.25 nM.

  Catalog
Abmole Inhibitor Catalog




Keywords: ATM Inhibitor-9 supplier, ATM/ATR, inhibitors, activators

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