Free shipping on all orders over $ 500

CP-466722

Cat. No. M2309

All AbMole products are for research use only, cannot be used for human consumption.

CP-466722 Structure
Synonym:

CP466722

Size Price Availability Quantity
1mg USD 35  USD35 In stock
5mg USD 85  USD85 In stock
10mg USD 145  USD145 In stock
50mg USD 385  USD385 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Cp-466722 is a reversible ATM inhibitor with IC50 value of 4.1 μM, but has no effect on PI3K, PIKK family proteins.

Chemical Information
Molecular Weight 349.35
Formula C17H15N7O2
CAS Number 1080622-86-1
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mei Hua Jin, et al. ATM in DNA repair in cancer

[2] Rodrigo Martinez-Monedero, et al. GluA2-Containing AMPA Receptors Distinguish Ribbon-Associated from Ribbonless Afferent Contacts on Rat Cochlear Hair Cells

[3] Aditi Nadkarni, et al. ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells

[4] Michael D Rainey, et al. Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation

Related ATM/ATR Products
ART0380 

ART0380 is a potent and selective ATR kinase inhibitor.

KU 59403 

KU 59403 is a potent ATM inhibitor, with IC50 values of 3 nM, 9.1 μM and 10 μM for ATM, DNA-PK and PI3K, respectively.

SKLB-197 

SKLB-197 showed an IC50 value of 0.013 μM against ATR but very weak or no activity against other 402 protein kinases.

ATR-IN-4 

ATR-IN-4 is a potent ATR (Ataxia telangiectasia mutated gene Rad 3-associated kinase) inhibitor.

M3541 

M3541 is a potent, ATP-competitive and selective ATM inhibitor with an IC50 of 0.25 nM.

  Catalog
Abmole Inhibitor Catalog




Keywords: CP-466722, CP466722 supplier, ATM/ATR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.