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Arzoxifene

Cat. No. M28924

All AbMole products are for research use only, cannot be used for human consumption.

Arzoxifene Structure
Synonym:

LY353381; SERM III

Price and Availability

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Quality Control & Documentation
Biological Activity

Arzoxifene (LY353381) is an orally active selective estrogen receptor modulator with a fixed ring structure similar to raloxifene. Arzoxifene has minimal side effects with powerful antiestrogenic effects on breast cancer and endometrium, with equally strong favorable estrogenic effects on bone and lipid profile.

Chemical Information
Molecular Weight 475.6
Formula C28H29NO4S
CAS Number 182133-25-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] D L Kendler, et al. Osteoporos Int. Arzoxifene versus raloxifene: effect on bone and safety parameters in postmenopausal women with osteoporosis

[2] Pamela N Munster. Expert Opin Investig Drugs. Arzoxifene: the development and clinical outcome of an ideal SERM

[3] Michael B Sporn. Clin Cancer Res. Arzoxifene: a promising new selective estrogen receptor modulator for clinical chemoprevention of breast cancer

[4] Cristina Marchisano-Karpman, et al. IDrugs. Arzoxifene Eli Lilly

[5] Thomas W Burke, et al. Gynecol Oncol. Arzoxifene as therapy for endometrial cancer

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  Catalog
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Keywords: Arzoxifene, LY353381; SERM III supplier, Estrogen Receptor, inhibitors, activators

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