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Arundic Acid

Cat. No. M14654

All AbMole products are for research use only, cannot be used for human consumption.

Arundic Acid Structure
Synonym:

ONO-2506; (R)-2-Propyloctanoic acid

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Quality Control & Documentation
Biological Activity

Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid has the potential for stroke and Alzheimer’s disease research.

Chemical Information
Molecular Weight 186.29
CAS Number 185517-21-9
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Adriana Fernanda K Vizuete, et al. Arundic acid (ONO-2526) inhibits stimulated-S100B secretion in inflammatory conditions

[2] J L Cordeiro, et al. Arundic Acid (ONO-2506), an Inhibitor of S100B Protein Synthesis, Prevents Neurological Deficits and Brain Tissue Damage Following Intracerebral Hemorrhage in Male Wistar Rats

[3] Pratap Karki, et al. Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK, Akt, and NF-κB Pathways

[4] Rodney A Fernandes, et al. Arundic acid a potential neuroprotective agent: biological development and syntheses

[5] T Asano, et al. Arundic acid (ONO-2506) ameliorates delayed ischemic brain damage by preventing astrocytic overproduction of S100B

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Keywords: Arundic Acid, ONO-2506; (R)-2-Propyloctanoic acid supplier, inhibitors, activators

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