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APcK 110 is a kIT inhibitor; inhibits phosphorylation of KIT, STAT3, STAT5 and Akt. Suppresses proliferation of OCI/AML3 cells (IC50 = 175 nM). Caspase-dependant apoptosis inducer.
| Molecular Weight | 349.36 |
| Formula | C20H16FN3O2 |
| CAS Number | 1001083-74-4 |
| Solubility (25°C) | DMSO 34.94 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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