Free shipping on all orders over $ 500

AP20187

Cat. No. M13547

All AbMole products are for research use only, cannot be used for human consumption.

AP20187 Structure
Synonym:

B/B Homodimerizer

Size Price Availability Quantity
5mg USD 320  USD320 In stock
10mg USD 500  USD500 In stock
25mg USD 950  USD950 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

AP20187 (B/B Homodimerizer) is a cell-permeable ligand used to dimerize FK506-binding protein (FKBP) fusion proteins and initiate biological signaling cascades and gene expression or disrupt protein-protein interactions.

Chemical Information
Molecular Weight 1482.75
CAS Number 195514-80-8
Solubility (25°C) Ethanol 100 mg/mL
DMSO ≥ 57 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mikolaj Ogrodnik, et al. Aging Cell. Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice

[2] Xiaobing Yu, et al. Nat Commun. Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain

[3] Mikolaj Ogrodnik, et al. Cell Metab. Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis

[4] Darren J Baker, et al. Nature. Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan

[5] Darren J Baker, et al. Nature. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

Related Products
DSPE-PEG-FA

DSPE-PEG2K-FA is a PEG derivative containing folic acid. DSPE-PEG2K-FA has a targeting effect and can bind to folic acid receptors in cancer cells. DSPE-PEG2K-FA forms micelles/lipid bilayers and can be used in research on targeted drug delivery systems.

Lifastuzumab

Lifastuzumab is a humanized anti-NaPi2b IgG1 monoclonal antibody.

GPVI antagonist 1

GPVI antagonist 1 is a glycoprotein VI (GPVI) platelet receptor antagonist. GPVI antagonist 1 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM.

MPSD TFA

MPSD TFA (MARCKS-ED TFA) is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS). MPSD TFA can sense membrane curvature and recognize phosphatidylserine. MPSD TFA can be utilized as biological probe to study membrane shape and lipid composition.

4-Nitro-2,1,3-benzoselenadiazole

4-Nitro-2,1,3-benzoselenadiazole is a biochemical material that can be used in scientific research.

  Catalog
Abmole Inhibitor Catalog




Keywords: AP20187, B/B Homodimerizer supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.