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Antimycin A1

Cat. No. M14464

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Antimycin A1 Structure
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Biological Activity

Antimycin A1 is a specific electron transfer inhibitor of ubiquinol-cytochrome c oxidoreductase. Antimycin A1 inhibits angiogenesis through decrease in VEGF production caused by inhibition of HIF-1α activation.

Chemical Information
Molecular Weight 548.63
CAS Number 642-15-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Asif Fazal, et al. A Standalone β-Ketoreductase Acts Concomitantly with Biosynthesis of the Antimycin Scaffold

[2] Rebecca Joynt, et al. A phylogenetic and evolutionary analysis of antimycin biosynthesis

[3] Nikolaos D Georgakopoulos, et al. The pharmacological regulation of cellular mitophagy

[4] Joyce Liu, et al. Antimycin-type depsipeptides: discovery, biosynthesis, chemical synthesis, and bioactivities

[5] Masayuki Maeda, et al. Inhibition of angiogenesis and HIF-1alpha activity by antimycin A1

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Keywords: Antimycin A1 supplier, inhibitors, activators

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