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Ag-024322 is a potent ATP-competitive pan-CDK inhibitor that inhibits THE Ki values of CDK1, CDK2, and CDK4 in the 1-3 nM range. Ag-024322 showed broad spectrum antitumor activity and clear target regulation in vivo. Ag-024322 induced apoptosis.
| Molecular Weight | 418.44 |
| Formula | C23H20F2N6 |
| CAS Number | 837364-57-5 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Kuo-Chen Chou. Curr Drug Metab. Graphic rule for drug metabolism systems
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