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AdipoRon hydrochloride is a agonist of adiponectin receptors AdipoR1 and AdipoR2 (Kd values are 1.8 and 3.1 μM respectively). Activates AMPK and PPARα signaling; ameliorates insulin resistance, dyslipidemia and glucose intolerance in db/db mice. Orally active antidiabetic agent.
| Molecular Weight | 464.98 |
| Formula | C27H28N2O3.HCl |
| CAS Number | 1781835-20-8 |
| Solubility (25°C) | DMSO 46.5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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