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Acetyl coenzyme A

Cat. No. M39099

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Acetyl coenzyme A Structure

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Quality Control & Documentation
Biological Activity

Acetyl-coenzyme A (Acetyl-CoA) regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A is also a key precursor of lipid synthesis.

Chemical Information
Molecular Weight 809.57
Formula C23H38N7O17P3S
CAS Number 72-89-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] David A Guertin et al. Nat Rev Cancer. Acetyl-CoA metabolism in cancer

[2] Adrian Drazic et al. Biochim Biophys Acta. The world of protein acetylation

[3] Harmen M van Rossum et al. Metab Eng. Engineering cytosolic acetyl-coenzyme A supply in Saccharomyces cerevisiae: Pathway stoichiometry, free-energy conservation and redox-cofactor balancing

[4] Federico Pietrocola et al. Cell Metab. Acetyl coenzyme A: a central metabolite and second messenger

[5] Luciano Galdieri et al. Eukaryot Cell. Protein acetylation and acetyl coenzyme a metabolism in budding yeast

Related Metabolite/Endogenous Metabolite Products
D-Tryptophan

D-Tryptophan is the D-isomer of tryptophan, as a non-protein active amino acid, has special physiological properties, can be used as additives, plant growth agents, etc. In the pharmaceutical industry, it is mainly used in the synthesis of various polypeptides, instead of L-tryptophan to extend the peptide half-life.

Arachidonic acid sodium salt

Arachidonic acid sodium salt (Sodium Arachidonate) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid sodium salt also acts as the substrate for various lipid mediators, such as prostaglandins (PGs).

trans-Vaccenic acid

trans-Vaccenic acid is a naturally occurring trans fatty acid (TFA). trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated Linoleic acid (CLA) at the tissue level. trans-Vaccenic acid inhibits nasopharyngeal carcinoma (NPC) cell growth and induces apoptosis through the inhibition of Bad/Akt phosphorylation.

Mead acid

Mead acid (5,8,11-Eicosatrienoic acid) is an unsaturated (Omega-9) fatty acid.

p-Cresol glucuronide

p-Cresol glucuronide is a metabolite of p-cresol, it is a prototype protein-bound uremic toxin.

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Keywords: Acetyl coenzyme A supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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