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ACET is a potent and selective GluR5-containing kainate receptor antagonist (IC50 = 7 nM) that displays selectivity over GluR6-containing kainate, NMDA, AMPA and group I mGlu receptors. Reversibly blocks induction of NMDA receptor-independent long term potentiation (LTP) in vitro at nanomolar concentrations.
| Molecular Weight | 429.45 |
| Formula | C20H19N3O6S |
| CAS Number | 936095-50-0 |
| Solubility (25°C) | 3eq. NaOH 8.59 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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