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Acepromazine maleate

Cat. No. M7602

All AbMole products are for research use only, cannot be used for human consumption.

Acepromazine maleate Structure

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Quality Control & Documentation
Biological Activity

Acepromazine is a phenothiazine antipsychotic compound commonly used as a veterinary drug (horse, dog, and cat). The compound is a similar antipsychotic compound chlorpromazine (#C8138). The drug is thought to block dopamine receptors in the brain. Recently, the compound was found to inhibit the expression of the ABCG2 transporter, whose overexpression in tumors is associated with drug resistance.

Chemical Information
Molecular Weight 442.53
Formula C19H22N2OS · C4H4O4
CAS Number 3598-37-6
Solubility (25°C) Water: ≥10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Robert J Brosnan, et al. Evaluation of whether acepromazine maleate causes fentanyl to decrease the minimum alveolar concentration of isoflurane in cats

[2] Julia P P Rangel, et al. Hemodynamic effects of incremental doses of acepromazine in isoflurane-anesthetized dogs

[3] Callie E Cazlan, et al. Effects of 2% lidocaine hydrochloride solution as a coinduction agent with propofol on cardiopulmonary variables and administered propofol doses in healthy dogs premedicated with hydromorphone hydrochloride and acepromazine maleate

[4] Fiona I Schneiders, et al. Acepromazine pharmacokinetics: a forensic perspective

[5] Karen M Tobias, et al. A retrospective study on the use of acepromazine maleate in dogs with seizures

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Keywords: Acepromazine maleate supplier, inhibitors, activators

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