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Acarbose (BAY G 5421) is an alpha-glucosidase inhibitor with oral activity (IC50=11 nM). Acarbose can enhance the hypoglycemic effect of sulfonylurea inhibitors or insulin.
| Molecular Weight | 645.6 |
| Formula | C25H43NO18 |
| CAS Number | 56180-94-0 |
| Solubility (25°C) | DMSO 89 mg/mL Water 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Linling Que, et al. Acarbose bioequivalence: Exploration of eligible protocol design
[4] Sherry G Dodds, et al. Acarbose improved survival for Apc +/Min mice
| Related Glucosidase Products |
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| Afegostat tartrate
Afegostat tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity. |
| Demethylisoencecalin
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| 3-Hydroxybakuchiol
3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. |
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