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ABT 724 trihydrochloride

Cat. No. M6390

All AbMole products are for research use only, cannot be used for human consumption.

ABT 724 trihydrochloride Structure

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Quality Control & Documentation
Biological Activity

ABT 724 trihydrochloride is a potent dopamine D4 receptor partial agonist (EC50 = 12.4 nM; 61% efficacy vs. dopamine). Has no agonist activity at D2 receptors (EC50 > 10 μM). Selective in rats in vivo; produces penile erection following i.c.v. administration; increases intracavernosal pressure and potentiates the proerectile effects of sildenafil following s.c. administration. Displays minimal side effects.

Chemical Information
Molecular Weight 402.75
Formula C17H19N5.3HCl
CAS Number 587870-77-7
Solubility (25°C) Water 40.27 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shiohara, et al. Blood. Effects of novel RAR- and RXR-selective retinoids on myeloid leukemic proliferation and differentiation in vitro.

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