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Abr-238901 is an orally effective S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE (receptor for advanced glycation end products) and TLR4(Toll-like receptor 4). Abr-238901 has the potential to be used in myocardial infarction (MI) research.
| Molecular Weight | 394.63 |
| Formula | C11H9BrClN3O4S |
| CAS Number | 1638200-22-2 |
| Solubility (25°C) | DMSO ≥ 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Goran Marinković, et al. Circ Res. S100A9 Links Inflammation and Repair in Myocardial Infarction
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